Barrett’s Esophagus and Cancer and GERD

Barrett’s Esophagus and Cancer

Barrett’s esophagus is a precancerous condition showing intestinal metaplasia of the lower esophagus and mucosecretory cells on histologic examination. It is the precursor to esophageal adenocarcinoma. Approximately 8%–10% of individuals with GERD have Barrett’s esophagus. In fact, the cancer risk for an individual with Barrett’s esophagus is 30 times higher than in the general population. Risk factors for Barrett’s esophagus include GERD for at least five years’ duration, male gender, Caucasian race, and age over 50.39 A study with U.S. veterans showed that GERD increases the risk of both laryngeal and pharyngeal cancers independent from other risk factors.( Stoltey J, et al , 2007)